The C-cells: current concepts on normal histology and hyperplasia
Vol. 45 No. Cumulative Issue 1999-2004, 2004
ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY
Angela Borda, Nicole Berger, M. Turcu, M. Al Jaradi, Sorana Veres
We describe the current concepts on the embryology, normal morphology and immunohistochemistry of a minor cell population of the thyroid, the C-cells. We also try to make delineation between the normal number of the C-cells and C-cell hyperplasia. The two types of C-cell hyperplasia, physiologic and neoplastic are defined and characterized from morphologic and genetic point of view. Their relation with thyroid pathology, especially with medullary thyroid carcinoma is discussed.
Corresponding author: Angela Borda, MD, PhD, e-mail: aborda2001@yahoo.com
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